Set amidst growing global challenges and great power politics, this article asks how middle powers might best promote global collective action. Adopting a historical approach, it explores four case studies on middle power multilateralism in (1) post-1974 UN New International Economic Order; (2) post-1989 Bretton Woods institutions; (3) post-1992 European Union expansion; and (4) post-2003 UN South- South cooperation. These inform a policy framework and an ensuing alternative termed “resilient multilateralism.” Adopting a foreign policy standpoint, this alternative entails principles on context specificity, complementarity, consensus building, and non-confrontation. By opening space for global action, it offers a timely approach to countering future shocks and coordination failures—whether wrought through nature or through hands of our own.